A Systemic Review on Adverse Effects Precipitated by Phenytoin and Its Management

Abstract

The incidence rate of phenytoin-induced gingival overgrowth varies from 3%to 93 percent, however gingival
overgrowth affects 50% of patients on long-term treatment. It takes 2–3months for the overgrowth to become
evident, and 12–18 months for it to reach its maximum severity. Partial relief is frequently achieved by lowering the
dose or substituting an appropriate medicine of complete regression of the lesion and can be considered after a
physician consult. The case study discusses on the appearance of phenytoin-induced gingival overgrowth in a
patient on phenytoin.