A CASE STUDY ON STEROIDS INDUCED CUSHINGSYNDROME AND IT'S MANAGEMENT

Abstract

Cushing syndrome is characterised by elevated cortisol or other exogenous glucocorticoid levels in the blood. Due to either an adrenal tumour or the pituitary glands over secretion of adrenocorticotropic hormone, this can be endogenous or iatrogenic cortisol secretion. Depending on the origin of Cushing syndrome, the pathophysiological process varies. Themost frequent cause of Cushing syndrome is prolonged use of exogenous gluco-corticoid hormones, particularlyin the treatment of lymph proliferative diseases at levelsof greater dosages. Long-term use of glucocorticoids isassociated with a number of systemic side effects,including Cushing's syndrome, cataract, hypertension,dyslipidemia, skin atrophy,failure to thrive, hypothalamopituitary- adrenal axis suppression, striae,glaucoma, and apropensity for life-threateninginfections.